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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ILKAP All Species: 24.85
Human Site: T352 Identified Species: 39.05
UniProt: Q9H0C8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0C8 NP_110395.1 392 42907 T352 L E D E K I Q T R E G K S A A
Chimpanzee Pan troglodytes XP_001152781 553 60157 T513 L E D E K I Q T R E G K S A A
Rhesus Macaque Macaca mulatta XP_001094705 590 64766 T550 L E D E K I Q T R E G K S A V
Dog Lupus familis XP_543305 401 43921 S352 L E D E K I Q S R E G K P T V
Cat Felis silvestris
Mouse Mus musculus Q8R0F6 392 42756 T352 L E D D K I Q T R E G K P A V
Rat Rattus norvegicus Q9Z1Z6 392 42726 T352 L E D E K I Q T R E G K P A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513557 590 63726 T395 L E D E K I Q T R E G K S A A
Chicken Gallus gallus XP_422661 389 42657 K349 L E D K N I Q K R E G K Q E A
Frog Xenopus laevis NP_001086890 344 37998 D306 E K S P S A E D G Q P D L D S
Zebra Danio Brachydanio rerio NP_001082973 129 14081 W91 A S S Q K P A W K D G S T A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496370 242 26827 G204 A G A V V K D G R I N G V I E
Sea Urchin Strong. purpuratus XP_001180671 354 39861 K316 N D I L D G E K V K Q S E G K
Poplar Tree Populus trichocarpa XP_002321498 266 28901 L228 A V E F V Q K L L K E G L T V
Maize Zea mays NP_001130289 360 39005 N322 D A V E F V Q N Q L K E T S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMT1 351 38467 K312 D A V G F V Q K L L K E G L H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.3 65 94.2 N.A. 95.1 95.1 N.A. 60.1 84.1 58.1 23.7 N.A. N.A. N.A. 28.8 47.7
Protein Similarity: 100 70.5 65.2 95.2 N.A. 97.6 96.9 N.A. 62.8 88.5 72.6 29.3 N.A. N.A. N.A. 42.5 65
P-Site Identity: 100 100 93.3 73.3 N.A. 80 86.6 N.A. 100 66.6 0 20 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 93.3 80 N.A. 86.6 86.6 N.A. 100 73.3 26.6 46.6 N.A. N.A. N.A. 6.6 20
Percent
Protein Identity: 26.7 33.1 N.A. 32.4 N.A. N.A.
Protein Similarity: 38.2 53.8 N.A. 52.8 N.A. N.A.
P-Site Identity: 0 13.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 53.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 14 7 0 0 7 7 0 0 0 0 0 0 47 27 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 7 54 7 7 0 7 7 0 7 0 7 0 7 0 % D
% Glu: 7 54 7 47 0 0 14 0 0 54 7 14 7 7 7 % E
% Phe: 0 0 0 7 14 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 7 0 7 0 7 7 0 60 14 7 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 7 0 0 54 0 0 0 7 0 0 0 7 0 % I
% Lys: 0 7 0 7 54 7 7 20 7 14 14 54 0 0 7 % K
% Leu: 54 0 0 7 0 0 0 7 14 14 0 0 14 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 7 0 0 7 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 7 0 7 0 0 0 0 7 0 20 0 0 % P
% Gln: 0 0 0 7 0 7 67 0 7 7 7 0 7 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 % R
% Ser: 0 7 14 0 7 0 0 7 0 0 0 14 27 7 14 % S
% Thr: 0 0 0 0 0 0 0 40 0 0 0 0 14 14 7 % T
% Val: 0 7 14 7 14 14 0 0 7 0 0 0 7 0 34 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _